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HOW EVENING PRIMROSE OIL WORKS IN RAYNAUD'S SYNDROME AND SCLERODERMA

Evening primrose oil was tried in Raynaud's syndrome because it makes PGEl in the body naturally. PGEl as a drug has been used effectively in Raynaud's syndrome, showing an increase in hand temperature for up to six weeks. In other words, the hands felt hotter. Normally, a patient suffering from Raynaud's syndrome has abnormally cold hands.
However, the problem with the drugs PGEl and prostacyclin is that they have to be given intravenously and repeatedly in hospital. The hope was that evening primrose oil could achieve the same effect without the inconvenience. Indeed, the results of the Glasgow trial did show that evening primrose oil produced the same results as the infused drugs.
Apart from being a precursor of Prostaglandin El, evening primrose oil has also been shown to increase the production of prostacyclin and to decrease levels of thromboxane B2, which constricts blood vessels. Also, evening primrose oil lowers vascular reactivity, and may suppress chronic inflammation in animals.
As an essential fatty acid, evening primrose oil also works in the body by helping to keep cell membranes fluid and flexible. This is an important function in a disease such as Raynaud's syndrome. Also, unsaturated fatty acids do not solidify in the cold - which is also an asset in Raynaud's syndrome. Patients who have both Raynaud's syndrome and scleroderma have found to be abnormally low in Prostaglandin El.

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GENERAL HEALTH

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