Generic Zantac

EVENING PRIMROSE OIL AND SCLERODERMA

The rationale for using evening primrose oil for scleroderma is the same as for Raynaud's syndrome.
The vascular complications of scleroderma may be successfully treated by infusions of prostaglandins which dilate the blood vessels. However, this treatment is impractical for long-term use.
A placebo-controlled study was carried out in which evening primrose oil or a placebo was given to patients. The researchers were looking for the fatty acid concentrations in plasma and red cells, and some particular prostaglandin concentrations in plasma.
Evening primrose oil produced a small and not significant rise in the concentrations of PGEl and PGE2 and a significant fall in the concentration of thromboxane B2. Treatment also elevated the concentrations of dihomo-gammalinolenic acid and arachidonic acid in plasma. These changes went with clinical improvement.
In patients with scleroderma there seems to be some abnormality in the conversion of essential fatty acids to prostaglandins. Evening primrose oil may be able to help correct this.

*44/60/5*
GENERAL HEALTH

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
• Read the product information leaflet provided with the product before using it.

   

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