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MULTI-INFARCT DEMENTIA: ASSESSMENT AND PREVENTION

Despite the picture given above it can still be difficult distinguishing between multi-infarct and Alzheimer's dementia. The initial assessment always includes a detailed medical and personal history. In multi-infarct dementia there is often a strong family history of heart attacks and strokes, especially on the male side. The younger the age that these events occurred the more relevant they become. There may be a history of smoking and of high blood pressure (hypertension) as well as chest pains (angina) and/or leg pains (claudication). Heart attacks (myocardial infarction) and strokes (cerebrovascular accidents) may have already occurred. A step-wise decrease in mental faculties associated with other evidence of a stroke help make the diagnosis. Doctors look for the evidence of other blood vessels having furred-up (the ones in the brain don't do it alone). A score is built up of likely linked events named after the man who invented it - the Hachinski score. The higher the score the more likely the mental impairment is due to multi-infarct dementia.
From the previous discussion it can be seen that there are risk factors for multi-infarct dementia in particular and strokes in general. Smoking, high blood pressure, excess fats in the blood (hyperlipidaemia and hypercholesterolaemia), obesity and a strong family history are relative risk factors. That means that within reason one can do something about them. One can't chose one's parents and grandparents but if they died from heart attacks or strokes when young then one should go to the doctor and have a full screen performed. High blood pressure can be lowered and smoking can be stopped, blood fats controlled and weight lost.
Once the damage has been done over many years it is often difficult to remedy. Following one stroke others still occur because the underlying problem (furred blood vessels) is still there. Some conditions such as sugar diabetes (diabetes mellitus) have an increased risk of stroke occurrence. In some people it may be possible to prevent further strokes occurring. Firstly, as many risk factors as possible are treated. In some people the furred-up blood vessels can literally undergo a re-bore to stop further blood clots forming on the furred-up surface. The blood can be made less sticky by the use of various drugs. Low dose aspirin is commonly used now to try and prevent mini-strokes (transient ischemic attacks). More rarely blood clotting is stopped by the use of the drug warfarin. There is some evidence that red wine may have a protective effect by increasing the amount of fat removed from the artery lining, the amount of red wine per day is disputed.
It must be hoped that as we become healthier in terms of diet, exercise and preventative medicine, then multiple strokes and multi-infarct dementia will become much less common.

*44/128/5*
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